{"id":2632,"date":"2024-01-05T18:11:25","date_gmt":"2024-01-05T10:11:25","guid":{"rendered":"https:\/\/www.aepromed.com\/?p=2632"},"modified":"2024-01-23T17:55:34","modified_gmt":"2024-01-23T09:55:34","slug":"inhaled-medications-for-systemic-treatment-unlocking-the-potential-of-pulmonary-drug-delivery","status":"publish","type":"post","link":"https:\/\/www.aepromed.com\/2024\/01\/05\/inhaled-medications-for-systemic-treatment-unlocking-the-potential-of-pulmonary-drug-delivery\/","title":{"rendered":"\u3010Inhaled Medications for Systemic Treatment: Unlocking the Potential of Pulmonary Drug Delivery\u3011"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"2632\" class=\"elementor elementor-2632\">\n\t\t\t\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-44be4736 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"44be4736\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-1c43cb54\" data-id=\"1c43cb54\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-5d8e33ee elementor-widget elementor-widget-text-editor\" data-id=\"5d8e33ee\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.13.0 - 08-05-2023 *\/\n.elementor-widget-text-editor.elementor-drop-cap-view-stacked .elementor-drop-cap{background-color:#69727d;color:#fff}.elementor-widget-text-editor.elementor-drop-cap-view-framed .elementor-drop-cap{color:#69727d;border:3px solid;background-color:transparent}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap{margin-top:8px}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap-letter{width:1em;height:1em}.elementor-widget-text-editor .elementor-drop-cap{float:left;text-align:center;line-height:1;font-size:50px}.elementor-widget-text-editor .elementor-drop-cap-letter{display:inline-block}<\/style>\t\t\t\t<!-- wp:paragraph -->\n<p>Did you know that inhaled drug delivery has emerged as a promising avenue for systemic treatment? Leveraging the expansive alveolar area of the lungs, inhaled medications can efficiently enter the systemic circulation, offering a novel approach to achieving therapeutic effects. Let&#8217;s explore the three key types of drugs currently formulated for inhalation:<\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:paragraph -->\n<p>(1) Fast-Acting Small Molecule Drugs:<br>*These drugs, with a molecular weight below 1000 Daltons, demonstrate rapid absorption by alveolar cells through inhalation.<br>*Lipid-soluble compounds can penetrate cellular membranes, while lipid-insoluble ones navigate through aqueous pores in tight junctions.<br>*Market examples include Adasuve\u00ae for psychiatric disorders and Levadex\u00ae for pain control.<\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:paragraph -->\n<p>(2) Peptide and Protein Drugs:<br>*Despite lower and slower absorption efficiency compared to small molecules, advancements are being made.<br>*Pulmozyme\u00ae addresses pulmonary cystic fibrosis, while ongoing research explores applications for anemia, multiple sclerosis, infertility, growth hormone deficiency, etc.<\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:paragraph -->\n<p>(3) Vaccines:<br>*Inhaled vaccines, like those for measles and rubella, are particularly beneficial in developing countries, eliminating needle-related disposal issues.<br>*Research indicates superior efficacy of inhaled rubella vaccines, showcasing improved immune responses and lower side effects.<br>*The pharmaceutical industry is actively developing inhalation routes for both small molecule and biologic drugs.<\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:paragraph -->\n<p>AeproMED Innovation Co. LTD.&#8217;s AirHyper Platform (AHP) stands out as an efficient drug delivery platform, significantly reducing the development time for inhaled drugs.<\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:paragraph -->\n<p><a href=\"https:\/\/www.linkedin.com\/feed\/hashtag\/?keywords=keyterms&amp;highlightedUpdateUrns=urn%3Ali%3Aactivity%3A7145334084985139200\">#KeyTerms<\/a>:<br>Dalton (Da): A unit of weight for atoms and molecules.<br>Peptide: A chain substance composed of 2 to 50 amino acids.<br>Neutralizing Antibodies Titer: Determined by diluting serum and testing its ability to neutralize the virus. A higher dilution factor retaining neutralizing power indicates a higher titer.<\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:paragraph -->\n<p><a href=\"https:\/\/www.linkedin.com\/feed\/hashtag\/?keywords=references&amp;highlightedUpdateUrns=urn%3Ali%3Aactivity%3A7145334084985139200\">#References<\/a>:<br>Ther Deliv. 2017 Jul;8(8):647-661.<br>Pharmaceutics 2020, 12, 1025.<br>Bull World Health Organ. 2002;80(10):806-12.<br>Can Respir J. 2018; 2018: 2732017.<br>Pharmaceutical Research (2023) 40:1037\u20131055<br>Pharm Res. 2023; 40(5): 1015\u20131036.&#8221;<\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:image {\"id\":2634,\"sizeSlug\":\"large\",\"linkDestination\":\"none\"} -->\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"576\" src=\"https:\/\/www.aepromed.com\/wp-content\/uploads\/2024\/01\/\u85e5\u7269\u61c9\u7528\uff08EN\uff09-1024x576.png\" alt=\"\" class=\"wp-image-2634\" srcset=\"https:\/\/www.aepromed.com\/wp-content\/uploads\/2024\/01\/\u85e5\u7269\u61c9\u7528\uff08EN\uff09-1024x576.png 1024w, https:\/\/www.aepromed.com\/wp-content\/uploads\/2024\/01\/\u85e5\u7269\u61c9\u7528\uff08EN\uff09-300x169.png 300w, https:\/\/www.aepromed.com\/wp-content\/uploads\/2024\/01\/\u85e5\u7269\u61c9\u7528\uff08EN\uff09-768x432.png 768w, https:\/\/www.aepromed.com\/wp-content\/uploads\/2024\/01\/\u85e5\u7269\u61c9\u7528\uff08EN\uff09-1536x864.png 1536w, https:\/\/www.aepromed.com\/wp-content\/uploads\/2024\/01\/\u85e5\u7269\u61c9\u7528\uff08EN\uff09.png 2000w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n<!-- \/wp:image -->\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Did you know that inhaled drug delivery has emerged as  &hellip;<\/p>\n<p class=\"read-more\"> <a class=\"\" href=\"https:\/\/www.aepromed.com\/2024\/01\/05\/inhaled-medications-for-systemic-treatment-unlocking-the-potential-of-pulmonary-drug-delivery\/\"> <span class=\"screen-reader-text\">\u3010Inhaled Medications for Systemic Treatment: Unlocking the Potential of Pulmonary Drug Delivery\u3011<\/span> \u7e7c\u7e8c\u95b1\u8b80 \u00bb<\/a><\/p>\n","protected":false},"author":3,"featured_media":2633,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"default","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","footnotes":""},"categories":[10],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v19.1 - 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